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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2e0119e5876ad71f6256eafb358fab4cd2a9a951aa3bea12c16cbc82ef8f1d' 
  AND token = '/RVQp+uL6bpg/LLi+OFv6rprUhaGv/wxaJfXHkGD7oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}