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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b5b754ed48746cc5c9a435cc66b3f86e6ce17d743bfea684f119c769b6dfc6' 
  AND token = 'Tb5z3Zlu9T4kk1zd+hoxinvBP3ek2IF2N1lI9dixg5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}