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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '744531cc3e81bdd40a261a9e23166e57b30a2ab86b5619b796dcea2d929a5808' 
  AND token = '3XLoA9+UhwoVEd11fWBWkeNYbxdBuWKQro1doCy9pNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}