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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c01e3cad39a718ee69e73f72fec2b4f7b7e38bcd9f5205fcf34b1892080192' 
  AND token = 'KptzVS9m4F+VsR+UWLc6iGkL0NkPR3A7gOGWHnYwdMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}