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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bbedd3c367a1d1ab920f1570d3424cde26150c1db34a25a6a39f1a72efcbbc0' 
  AND token = 'ok7pUy4VAKNC1OZWPJK9aEwszZxdjaCK3wUDMoWAbIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}