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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfbb2aeaedac46ef578261025c97ea6566611d0c465918f7f407489ad41ca535' 
  AND token = 'co1QpLf6psttHiX8TVIHpL1wWXx2mOKUE8JPsj6/wwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}