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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df70ba6cdf48784aa84ffea1793f69da9d7f0cdd420c6e9fa94e32f19e6156e7' 
  AND token = 'JZyIaX4z3/X+OT7uWFRRxwV/+cNOkK2vS4ix6Jck7e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}