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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28b63669be9e366286e3236a11faf4732503f3f785220164ae3d19a7bdc2e6ae' 
  AND token = 'GnVZ/RWNJD46IqvlMK0EwAD9E/d+ngZEsBACpDAVSA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}