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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ed7f32ae120ee985c63a1a4f0e14dde04685fd1477902ab33fd2b3254d0131' 
  AND token = 'ThOls4aefVw8M7Sclre8UQ90wfxKIOkeW0utilAiLT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}