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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54179ce861721156c5d482cc8cc3a5902aa26d39440a543878308ae39fff8b0b' 
  AND token = 'X8GP7yJQSuEu4O//wt7scY/rIoOOP1OsvkY3M78h0us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}