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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bf8736a0929d3f0504e3be8b8ed8bf65d280708ca66284ee8eb3e7b713bc0c' 
  AND token = '/D0tjWQUQ+bV5PTI3EQj/HDOdSd765BvORzGlxSOLEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}