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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e10a8c0829593b57fea146a4b9cc555f251450471cc889f1a69d06b5f3298f' 
  AND token = 'XyS1G0G7YzovIYtGtwtAumTJqKohw0SVeEGGUTs+r6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}