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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c0dd7eb191fb89bb155922fe0270e1018848eb36106667e80be36daee1101bc' 
  AND token = 'frixPf8E60gT0Fo7g1X/RIDXqnRNsG5xJLPkJD2VJ60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}