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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2254da0ffde0cba676e386ab92d67a1ced4c303eb195d468487659773a096496' 
  AND token = 'Tr/12psY9U3lAYQEeC3LbarvZlPEiznqiQvV0aFWrcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}