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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c6a6098066d99564d0e657f9a5f9f236bee1f49c9da2304f6262822e404886a' 
  AND token = 'alZeXRTI0xcyxDUOVMC6vawm/pAmM7VgRZh59Z76P34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}