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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6a0756df4baa6f3f7f09501fdb726688f5450040102554f9c2b3c626028248' 
  AND token = 'iD7rcg2XWZP3z5DZan560Y/EN1g0pLs0v63WC+sN7/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}