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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d9ecd2436d44bc18acec049b1fb2042dc1a47453336c8fb4ed9944f4db07fec' 
  AND token = 'GpIWGYPzED7vfGJx33QZv9iaPv5O0MwoguZ+5Cz49IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}