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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e952387de55d56c26e096ea8cd81c7ff02f63c0220fc729ac026bcb664257a7' 
  AND token = 'BkMNiCmfi3rIeqBywH7M+hOJtBp9hzKFQbhr4VE2JAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}