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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0da51f7ab41c1c12300347dcb572efdf20b3b5b03dd339fe3b6dc7accde2c0' 
  AND token = 'uLizWBk5KfmDFVPsidt8ZNEjqWNjoHIXgHEEjMp66dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}