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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a049d1fe61679dc0fd1baf612de93f4e4a16ec03e374bd0a0d22c9f2d80ec814' 
  AND token = '+aLS9lRxUN/enlgzxHZY9sOnPcz1Qmlm0v4QBoWFYrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}