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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c603089451c317330a703b47e2040808daea56102e26c49e24d4f2048b52a63' 
  AND token = 'x/ZtwsenMnZXieiuQk7ggXK7OIiMS8gVPmnyqpojHQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}