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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e376321794ecaa20fc81bf8d713cac5f8476bc80ec90baccf5d385b6821f86b' 
  AND token = 'klj01VM9FkjO+fQdlQXEK2VklLeMlOwBQI1vts5O+JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}