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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97f48269ce5b7a27f73c721da977c3e8f956b2694d7edfd74aac50556a8856b3' 
  AND token = 'Ms8dnk2/E6QQiGJXUn3JQSKwX+CmLQbbiNS5BB22EqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}