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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4de4596ff05de3bc6b13394a90fd097e80bd5c3c1f5498edbb3476550aead20e' 
  AND token = 'EgVABvo+rdlfxmfIw7EWPrU2QYb88/LbAJ8v38gqvrA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}