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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd01be3def5a386275cc672710840382cfe90e7c945a824005d9ca1eedb1f3725' 
  AND token = 'v6WLloK0D+tRR03+hNoC3/4iz4txytL4Gopx7rDDzEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}