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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6048f7029aab6161ed771d73f94969647ea9b944d7c6e933651f5f790d448ce0' 
  AND token = 'LplL9M1zLOgiP7mKxdQ3Fxzjeu6yLU3oRAn48UxyE/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}