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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af14ac9a90e284d3cfc87817b0b1ebd74b0fb88c81d2b522869292273a2a461' 
  AND token = 'nQrMHY1ACU6mYpzabseCMedptZ01okUj1K7hbu1iFdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}