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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c240864e0705ba3eba34066c0d6d15820b7897d6e4e7b2fc7128edc388ad6ece' 
  AND token = 't+IR5JYnI/qTLdhqqNmiHhiSROnwKCqLUhz7rFY5y/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}