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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3bd10bfe4d1b2f2001789c80ac68c44811236c273aa4853a6dacbfafd688de' 
  AND token = 'yQKI9ELiH5JKWtfjtstsRPQe9+HoEPToBImVpGYbPCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}