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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4388f11211c518dd7d60eb179c5a0f7eafa569c5e896e1aa390d538265cf1b24' 
  AND token = 'tgt9r2y4IgTGLcLJ5rsMiHbfAFWP3tOzIcC3iRXE6UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}