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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6191759cbb8cd27a83c9b527c005789feae32be0b311bf9a8ddaa0d44c5f65a' 
  AND token = 'InUJ/lPfTrr0o0tkXL6DfR0aXjez1x9Fne+g7G2HYrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}