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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e327a59ba9ae6a719af1a6db106ebd284597d4402365b1406eb4196277f08956' 
  AND token = '4N+LESiDIXqIJWe9DmPD6aBIVHa/2dh/8dzG8hPiSzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}