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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c460eee10ba5482175097a54829cd4c8882d2a0bf3ca04ec6e7bb74e63181cef' 
  AND token = 'iRvyH8TZ0XXyZSMiZ9mT4QQjOYELAdXfdGdcErn1xAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}