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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03278dc12badd58ec50bfcd67495b814693ea5d8280aef6a1f479e2536daecb6' 
  AND token = 'Y+79/IFFzWP3k4OUUsMnqQyowmnIT4Xff7sJn5VkibA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}