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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3ed3331b75e348f0b00c8f0d1349a4bc3f539d3d64c9de5fe2c9d645e7b898' 
  AND token = 'sW5Jd2v2kjceQqPQUxjledcC71Pd0b00w+pR+d3nCNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}