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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '862e13b1e4cb02e94846fd33faffdf8e797154a117f644958ebbc6db9cf91498' 
  AND token = 'dobKLXJ25yy2wgfjcOF+zsdqvm0MAbgEDyfeDppI8AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}