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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c2c639489eccdabc3b1bbaea3f09b4f50f32d4c2f58355d6dfb16bc020e66ad' 
  AND token = 'GbD4XNHO4yrG8l4xE74BtI2UioQxuT+tCyAQHaTvdRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}