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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52aaca5bdfc01cae04d285ed987eea55b35dc28da1c0b0e5c758937da5bdd248' 
  AND token = '6wPLOcAmfF/9qhG5MrOA9pPc313xFktfcMGg/QwDTyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}