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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7b3071059e4be814654c8af98f1e2b1dee800b9d5ab5dfd7c65440627338511' 
  AND token = 'jV+Wb0uWNVUoYwei4OV3TscaXBEDIv/d4hjwyhNhYGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}