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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd04beb669dd8721f3dc7e442148ec088a78e214a892ac5c9fa43302a936e1227' 
  AND token = '5l2xPB0B6/BoTSmfNR/wDKmTf6jEFOxNGEh6c6vh0lU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}