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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162a6fab9748d62bfcc9820a1ab12acaf9cc18d94c1ac04d8829c35b26396e28' 
  AND token = 'uoD1EnPBPRXlKijFM1Dbud49LfnN3HVdJ1XrsWM74Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}