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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df2627c3f5c403249c1ca3338ef20bbee41f494907146ce69b59e69e9bb431ef' 
  AND token = 'VG1XXD7K/MmUWWdxCQC7MHQJ9GDwpGJ1kOaaZgDtozI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}