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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f9fedc19d44b12fb1e168894b607f67558e3eba6ccab860224895a00a24e84' 
  AND token = 'QVNB6oKrsllSTjrmVL2OcOMUCngMyJuNYFTOTBuz1wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}