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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0922c6e2819e4429ec911ce33aafb75087fe1c35436acfd74f39a1c66c294f70' 
  AND token = 'WuxqkL6FickhtAsFv9fFnCu3zPWOsAqd1ZcKz9/vK88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}