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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f6b565d1e9e2f5a5ad304408d475c757bab318c6650c61bf272c4ce5c550223' 
  AND token = 'Gn2s83tGuHZOoeUTYlSEK0fMu+yKJaAhe+VHnXjxXPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}