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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ad93f58788b1adfc6a74380bb81aa8079e8d6492bae29b7b6ed5110f917503' 
  AND token = 'JXvj7EFo2m/4pB8YtiW75bZN3Hkmf7YVm5LK6p2oprQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}