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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb6331f93e6bff5c82cfb79b15e9448f14b721443fe88d98caf6071a41d1a67' 
  AND token = 'NRHcOfQrkjuxL9dGk8OsOrfmGzvxTiMQOkDND+gpKVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}