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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f80d7fafd35f9bc9385c59c6a358faa14ce9cfe4556a6a3aa61886ee95cf538f' 
  AND token = 'ORkpeUUbbtycgWUCGUopAmIo4mjoMJgB+NG1Nt3ioY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}