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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6aa6bf048d1e478f528c5fc45d0b2760d4d8eb7d2db20819c9d2346976ac685' 
  AND token = 'Y19LWnSqHqbflHsv30ly978LkB7DdacD3ky7goOh+aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}