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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36440e5326c2ebb8ad7fd24b9ba7fe21aab6769b7dda537fa227890b88baa799' 
  AND token = 'eAt7AfDhiIhBO0YTy7f3GD6tCJ/tC8Ago2YW75DbiRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}